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If you’re managing persistent pain, surgical recovery, or chronic conditions, Hydrocodone 10/325mg (M367 / Norco 10mg) remains a time-tested solution trusted by healthcare professionals worldwide. Its balanced formula, combining strong opioid relief with the added comfort of Acetaminophen, provides both power and precision in pain control.

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Hydrocodone 10/325mg (M367) – Trusted Norco Pain Relief Tablets

Hydrocodone 10/325mg (M367), also known by its brand name Norco, is one of the most widely recognized and prescribed pain medications available today. Each tablet contains 10 milligrams of Hydrocodone bitartrate, a powerful opioid pain reliever, and 325 milligrams of Acetaminophen, a mild non-opioid analgesic that boosts Hydrocodone’s pain fighting power.

If you’ve been searching for real Hydrocodone M367 tablets or Norco 10/325mg for sale online, TegrityPharma.com offers pharmaceutical-grade, verified Hydrocodone that meets the highest quality and purity standards. Our products are authentic, lab-tested, and shipped discreetly, ensuring both safety and confidentiality from order to delivery.

Recognizing Hydrocodone 10/325mg Tablets

Hydrocodone 10/325mg comes in a variety of shapes and imprints, depending on the manufacturer. If you’ve ever searched for M367 pill, Watson 853 yellow pill, or IP 110 tablet, you’ve likely encountered different versions of this same medication. Here are a few of the most common imprints:

  • M367 – White, oblong tablet (Mallinckrodt)
  • Watson 853 – Yellow, capsule-shaped tablet (Watson Pharmaceuticals)  Buy Hydrocodone 10/325mg (M367) Online | Real Norco Pain Relief Tablets
  • U03 – White, oval tablet (Aurolife Pharma)
  • IP 110 – White, capsule-shaped tablet (Amneal)
  • Norco 539 – White, brand-name version

These identifiers help patients and caregivers distinguish between genuine Hydrocodone 10/325mg Pill and counterfeit versions. Searches like identify Hydrocodone pill, Hydrocodone 10/325mg tablet images, and pill imprint M367 meaning are common among those verifying their prescriptions.

Understanding Hydrocodone 10/325mg (M367)

The M367 imprint pill is a white, oblong shaped tablet containing Hydrocodone 10mg and Acetaminophen 325mg. Manufactured by Mallinckrodt Pharmaceuticals, this combination medication is a mainstay in pain management for patients suffering from chronic, severe, or post operative pain.

Hydrocodone is a semi synthetic opioid derived from codeine that works by binding to receptors in the brain and spinal cord to block pain signals. Acetaminophen, also known as Tylenol, increases the effectiveness of Hydrocodone while reducing inflammation and fever. Together, they provide rapid, balanced relief for pain that doesn’t respond to over-the-counter treatments.

Because of its strength, Hydrocodone 10/325mg M367 is generally prescribed for patients with higher pain tolerance or those who require long-term opioid therapy. Its fast onset and 4–6-hour duration make it ideal for sustained yet controlled pain relief throughout the day.

Hydrocodone 10/325mg (Norco) Overview

FeatureDetails
Brand NameNorco 10/325mg
Generic NameHydrocodone Bitartrate and Acetaminophen
Imprint CodeM367
Color/ShapeWhite oblong tablet
Strength10mg / 325mg
Drug ClassOpioid Analgesic
ScheduleSchedule II Controlled Substance
ManufacturerMallinckrodt Pharmaceuticals

What Is M367 Norco 10/325mg Used For?

Doctors commonly prescribe Oval Pill Norco M367 for conditions that cause moderate to severe pain. These can include post surgical recovery, dental pain, sports injuries, fractures, or long-term conditions such as arthritis and nerve pain.

Many patients who undergo surgery or experience trauma rely on Hydrocodone 10/325mg to restore comfort and mobility. It’s also used in palliative care settings for patients with cancer related pain or other chronic conditions that impact quality of life.

When taken as prescribed, M367 Norco can help patients regain normal function and reduce the constant discomfort that interferes with work, sleep, and daily activity. However, because Hydrocodone is an opioid, users must follow their doctor’s dosage instructions carefully to avoid dependence or side effects.

How Hydrocodone 10/325mg Works in the Body

Hydrocodone affects the central nervous system by binding to mu-opioid receptors, which are responsible for processing pain and pleasure. When activated, these receptors dampen pain signals sent to the brain, creating a sense of physical relief and calmness.

The Acetaminophen in m367 white oblong pill norco works on a different pathway, reducing inflammation and fever by inhibiting certain enzymes in the brain. The combination makes Hydrocodone more effective at lower doses while minimizing the need for stronger opioids like Oxycodone or Morphine.

Many users describe the experience as a gentle wave of pain relief rather than an overwhelming sedative effect, making it a preferred choice among patients seeking functional, clear headed pain management.

Side Effects and Safety Tips

Like all opioids, Hydrocodone 10/325mg comes with risks. Common side effects include:

  • Drowsiness
  • Dizziness
  • Nausea
  • Constipation
  • Lightheadedness

More serious risks include respiratory depression, liver damage (especially when combined with alcohol), and dependency. That’s why it’s classified as a Schedule II controlled substance powerful, but not to be taken lightly.

Searches like Hydrocodone 10/325mg side effects, is Norco addictive, and opioid safety guidelines reflect growing awareness around responsible pain management.

Methylphenidate Hydrochloride Duration, Dosage,

Most users begin to feel relief within 30–45 minutes after taking a Hydrocodone 10/325mg tablet. The effects generally last between 4 and 6 hours, depending on the individual’s metabolism, tolerance, and pain level.

The typical starting dose is one tablet every 4 to 6 hours as needed. Patients are advised not to exceed six tablets per day to prevent liver toxicity from Acetaminophen.

Taking Hydrocodone M367 on a consistent schedule allows for steady pain control throughout the day. It’s best taken with food to reduce nausea and should never be mixed with alcohol, benzodiazepines, or other sedatives.

Hydrocodone 10/325mg (M367) and Addiction Awareness

Because Hydrocodone is an opioid, long-term or high-dose use can cause tolerance and dependence. To prevent addiction:

  • Follow prescribed doses only.

  • Avoid combining with alcohol or benzos.

  • Store securely away from children or others.

  • Taper gradually under medical supervision.

If used responsibly, Hydrocodone 10/325mg Norco remains one of the safest, most effective options for short to medium term pain relief.

Identifying Real vs. Fake M367 Hydrocodone Pills

Counterfeit Norco pills have become increasingly common on the black market. Fakes may contain Fentanyl, Tramadol, or synthetic opioids making them dangerous and unpredictable.

How to Identify Genuine M367 Tablets

  • Imprint: “M367” clearly debossed on one side.  Buy Hydrocodone 10/325mg (M367) Online | Real Norco Pain Relief Tablets

  • Color: White to off-white.

  • Shape: Capsule or oblong.

  • Taste/Smell: Odorless, slightly bitter.

  • Texture: Smooth, non-chalky finish.

Fake Norco pills may crumble easily, smell chemical, or display uneven markings.

At Tegrity Pharma, all Hydrocodone 10/325mg tablets are pharmacy grade and batch verified for authenticity.

Hydrocodone Dosages Explained

Hydrocodone is available in a range of doses designed to match each patient’s level of pain tolerance and treatment needs. The most common prescription formulations combine Hydrocodone bitartrate with Acetaminophen (Paracetamol), and are identified by both their milligram strength and imprint codes.

Common Hydrocodone Dose Strengths

  • Hydrocodone 5/325mg (Norco 539 or M365) – Typically prescribed for mild to moderate pain, ideal for short-term use.

  • Hydrocodone 7.5/325mg (Norco 729 or M366) – A balanced option for patients requiring stronger pain control without excessive sedation.

  • Hydrocodone 10/325mg (Norco M367) – One of the highest available strengths, intended for severe or chronic pain where lower doses are ineffective.

Each tablet combines Hydrocodone (an opioid analgesic) with 325mg of Acetaminophen, which enhances pain relief and allows for lower opioid doses to be effective.

Immediate-Release vs Extended-Release Hydrocodone

Hydrocodone comes in both immediate-release (IR) and extended-release (ER) forms:

  • Immediate Release Hydrocodone (e.g., Norco, Lortab, Vicodin) provides fast pain relief, usually within 30–45 minutes, and lasts 4–6 hours.

  • Extended Release Hydrocodone (e.g., Zohydro ER, Hysingla ER) offers continuous pain management for up to 12 hours and is often prescribed for chronic pain conditions.

Most Hydrocodone 10/325mg tablets with M367 imprint are immediate-release, designed for short term relief and fast absorption.

Norco Medication Typical Dosing Schedule

Doctors usually recommend taking one Hydrocodone/Acetaminophen tablet every 4–6 hours as needed, depending on pain severity.
The maximum daily Acetaminophen limit should never exceed 3,000 to 4,000 mg, which means no more than 6–8 tablets per day, depending on strength.

Important Safety and Usage Notes

  • Always follow medical guidance—never increase your Hydrocodone dose without consulting your doctor.

  • Avoid combining with alcohol, benzodiazepines, or sleep medications, as these can cause dangerous respiratory depression.

  • Hydrocodone is habit-forming; take it only as prescribed and never share it with others.

  • If switching from Norco 5mg or 7.5mg to Norco 10mg (M367), your doctor will likely adjust the dose gradually to reduce withdrawal or sedation risk.

Whether you’re managing post-surgical pain, chronic back pain, or severe injury recovery, understanding Hydrocodone dosage is key to safe and effective relief. For verified, pharmacy-grade Hydrocodone M367 10/325mg, visit TegrityPharma.com a Trusted Online Pharmacy USA where authenticity, privacy, and medical reliability come first

How Long Does Norco 10/325mg Stay in Your System?

Norco 10/325mg, a combination of Hydrocodone and Acetaminophen, is one of the most commonly prescribed opioid pain relievers for managing moderate to severe pain. While it’s highly effective, understanding how long Norco stays in your system is essential—especially for individuals undergoing a drug test, monitoring dosage schedules, or managing Hydrocodone dependency.

Several factors affect how long Hydrocodone 10/325mg (also known by its pill imprint M367) remains detectable, including metabolism rate, liver health, hydration, and frequency of use.

Norco Detection Times by Drug Test Type

The detection window for Norco varies depending on the test method. Here’s a closer look at how long Hydrocodone and Acetaminophen can be traced in different testing systems:

  • Urine test: Norco can be detected for 2 to 4 days after the last dose.

  • Blood test: Detectable in the bloodstream for up to 24 hours.

  • Saliva test: Detectable for approximately 12 to 36 hours, depending on dosage and frequency.

  • Hair follicle test: The most long-term test, capable of detecting Norco use for up to 90 days.

These time frames apply to Hydrocodone 10mg / 325mg tablets such as Norco M367, but they can vary slightly based on individual physiology and drug tolerance.

Hydrocodone and Acetaminophen Half Life

Every medication has a biological half-life, which refers to the time required for the body to eliminate half of the dose.

  • Hydrocodone half-life: approximately 4 hours

  • Acetaminophen half-life: approximately 2 to 3 hours

In general, it takes about five to six half lives for a substance to be mostly cleared from the system. For Norco 10/325mg, this means that while Hydrocodone is typically eliminated from the bloodstream within 18 to 24 hours, metabolites and trace amounts may still be detectable for several days especially in urine and hair tests.

Key Factors That Influence How Long Norco Stays in Your System

The duration of Hydrocodone detection is not universal it depends on individual health and lifestyle factors. These include:

  • Liver function: Since both Hydrocodone and Acetaminophen are processed by the liver, impaired liver function can delay clearance.

  • Age and body composition: Older adults and those with higher body fat percentages tend to retain traces longer.

  • Dosage and frequency: Higher or more frequent doses of Norco 10/325mg naturally take longer to eliminate.

  • Hydration and kidney function: Proper hydration and healthy kidney performance help speed up excretion through urine.

People who use Norco 10/325mg regularly or in higher doses especially for chronic pain may find that Hydrocodone metabolites remain detectable for extended periods compared to occasional users.

Hydrocodone 10/325mg vs Norco 7.5/325mg vs Vicodin 5/500mg

StrengthHydrocodone ContentAcetaminophen ContentIdeal Use
Norco 5/325mg5mg325mgModerate pain relief
Norco 7.5/325mg7.5mg325mgModerate-to-severe pain
Norco 10/325mg (M367)10mg325mgSevere pain / chronic conditions

Patients who find lower dose Norco tablets insufficient often switch to 10/325mg M367, which provides stronger, sustained relief without requiring higher frequency dosing.

Hydrocodone 10/325mg vs Oxycodone 10/325mg (Percocet)

While both Norco and Percocet combine an opioid with Acetaminophen, the primary difference lies in potency and onset time. Oxycodone (Percocet) is slightly stronger and faster-acting, while Hydrocodone (Norco Medical) provides smoother, more balanced relief with fewer side effects like nausea.

Patients who find Oxycodone too intense often prefer Norco for daytime use, as it provides pain control without excessive sedation. Both medications are prescription-only and should be used responsibly under.

Hydrocodone 10/325mg vs Norco 5/325mg vs Norco 7.5/325mg

Hydrocodone is available in several strengths, with the 10/325mg M367 being the highest common formulation. Lower doses like 5/325mg or 7.5/325mg are often used for moderate pain or initial therapy.

Patients who find those doses ineffective or require stronger pain management for chronic conditions are typically transitioned to M367 Norco 10/325, which offers maximum relief without escalating opioid exposure.

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When you order from Tegrity Pharma, you’re not just buying pain relief you’re choosing peace of mind, reliability, and verified medical quality.

The Importance of Authenticity and Responsible Use

The rise of counterfeit opioids has made authenticity more important than ever. Illicit Hydrocodone lookalikes can contain lethal levels of Fentanyl, posing serious health risks. That’s why Tegrity Pharma works exclusively with certified manufacturers and FDA compliant suppliers.

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Reviews (2)

2 reviews for Hydrocodone 10/325mg (M367)

  1. Jacob Fuller – September 20, 2025

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